NMR Spectroscopy Services

Comprehensive NMR spectroscopy services with dual 500 MHz Bruker spectrometers and multiple specialized probes.

NuMega operates two high-field Bruker NMR spectrometers with interchangeable probe capabilities, enabling fast turnaround times and a wide range of 1D and 2D experiments for structure determination, purity analysis, and compound characterization.

Our NMR Instruments

Two 500 MHz Bruker NMR spectrometers at NuMega Resonance Labs

Dual 500 MHz Bruker Spectrometers

We operate two Bruker 500 MHz NMR systems:

Bruker Avance II 500
Bruker AV-500

Key Advantages

High resolution - 500 MHz provides excellent spectral clarity
Versatile capabilities - 1D, 2D, multinuclear experiments
Reliable performance - Bruker's industry-leading technology

NMR Probes Available

We have highly sensitive probes that can be tuned to a broad range of nuclei, providing exceptional flexibility:

Broadband Probe

Size: 5 mm
Nuclei: P-31, C-13, N-15, B-10, B-11, V-51, Sn-119, O-17, Li-7, Si-29, and more

QNP Probe

Size: 5 mm
Nuclei: H-1, F-19, C-13, P-31

NMR Experiments We Perform

1D NMR Experiments

Routine 1D NMR

H-1 NMR - Proton NMR (most common)
C-13 NMR - Carbon-13 with DEPTQ
P-31 NMR - Phosphorus-31
F-19 NMR - Fluorine-19

Specialized Nuclei

Si-29 NMR - Silicon-29 (silicones, siloxanes)
B-11 NMR - Boron-11 (boronic acids)
B-10 NMR - Boron-10 (if enriched)
V-51 NMR - Vanadium-51
Sn-119 NMR - Tin-119
N-15 NMR - Nitrogen-15 (if enriched)
O-17 NMR - Oxygen-17
Li-7 NMR - Lithium-7

Advanced 1D Techniques

Editing & Quantitation

DEPTQ - Detect quaternary carbons
DEPT-45, 90, 135 - Carbon multiplicity editing
APT - Attached proton test
Quantitative NMR - Purity determination

Specialized 1D

1D NOE - Nuclear Overhauser Effect
Water suppression - For aqueous samples
Decoupling experiments
Variable temperature (VT) NMR
Selective excitation

2D NMR Experiments

We perform a comprehensive range of 2D NMR experiments for complete structure elucidation:

Homonuclear 2D (H-H correlations)

COSY - Correlation Spectroscopy (H-H coupling)
TOCSY - Total Correlation Spectroscopy
NOESY - Nuclear Overhauser Effect Spectroscopy (spatial proximity)
ROESY - Rotating-frame Overhauser Effect Spectroscopy

Heteronuclear 2D (H-C correlations)

HSQC - Direct C-H bonds (1-bond correlations)
HMBC - Long-range C-H bonds (2-3 bond correlations)
HMQC - Heteronuclear Multiple Quantum Coherence

Custom NMR Experiments

We Can Run Your Specific Parameters

Have a specific pulse sequence or experimental parameters you need?

We can follow your exact acquisition parameters
Specialized experiments for unique applications
Method development and optimization
Sorry, at this time we do not run custom pulse programs

Don't see the experiment you need listed? Contact us to discuss how we can assist you. We're experienced with a wide range of NMR techniques and can likely accommodate your specific requirements.

Follow Our NMR Services

Check out our NMR Services LinkedIn Showcase page for updates, tips, and NMR insights: NuMega NMR Services on LinkedIn

Ready to Get Started with NMR Analysis?

Submit your samples for professional NMR spectroscopy

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Phone: (858) 793-6057 | Email: NuMegaLab@NuMegaLabs.com